Sunday, September 13, 2009

Treatment of constipation in adults

If you are constipated and not sure what to do, I have summarized here some general treatment for non severe constipation. First of all, you need to eat a diet rich in fiber (fruits, vegetables, grains), increase physical activity, and drink plenty of fluids throughout the day. The recommended amount of dietary fiber is 20 to 35 g/day. You can also use bulk Forming Laxatives (Psyllium, Methylcellulose, Calcium Polycarbophil). These are natural or synthetic polysaccharides (carbohydrates) that primarily absorb water and increase fecal mass; they may cause abdominal bloating and gas.

If you do not respond to dietary changes, you may require laxatives other than the bulk forming agents.
Stimulant Laxatives (Bisacodyl, Senna) are indicated for acute constipation. Bisacodyl suppositories work very rapidly. They may cause cramping, diarrhea; I would not recommend for long term use. Osmotic laxatives (Lactulose, PEG 3350, Glycerin, Sorbitol) and Saline Osmotic (Magnesium Citrate, Magnesium Hydroxide, Sodium/potassium phosphate) are another option but long term use is not recommended.

Stool Softeners (Docusate Sodium, Docusate Calcium, Docusate Potassium) have marginal efficacy in most cases of constipation; however, stool softeners are used to soften the stool. Therefore, they can be used as adjunct therapy to other laxative, for it is used to prevent straining and exacerbation of hemorrhoids. They should not be taken together with mineral oil.

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